Dry Powder for Pulmonary Delivery: A Comprehensive Review
نویسندگان
چکیده
منابع مشابه
Dry powder inhalers for pulmonary drug delivery.
The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However, they are also complicated systems, the the performa...
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In the recent years pulmonary drug delivery system is found to be preferred route of administration for various drugs. It has been divided into 3 classes: Nebulizers, pMDI, DPI.DPI are used as an alternative to pMDI because pMDI contains propellant (CFC) which has ozone depletion characteristics. DPI delivers medication in the form of dry powder to lungs. DPI is formulated either as a carrier b...
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PURPOSE Local therapy is a valuable and strategic approach in the treatment of lung associated diseases and dry powder inhalation (DPI) formulations play the key role in this plan. Transfersome has been introduced as a novel biocompatible vesicular system with potential for administration in pulmonary drug delivery. The present study was designed to prepare Itraconazole-loaded nanotrantransfers...
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This brief communication evaluates the cytotoxicity and targeting capability of a dry powder chemotherapeutic. Nano-in-microparticles (NIMs) are a dry powder drug delivery vehicle containing superparamagnetic iron oxide nanoparticles (SPIONs) and either doxorubicin (w/w solids) or fluorescent nanospheres (w/v during formulation; as a drug surrogate) in a lactose matrix. In vitro cytotoxicity wa...
متن کاملThe preparation and application of pulmonary surfactant nanoparticles as absorption enhancers in insulin dry powder delivery.
AIM To study the preparation and application of pulmonary surfactant (PS) nanoparticles as absorption enhancers in insulin dry powder delivery. PS is a complex mixture of mainly phospholipids and proteins. The composition leads to a unique spreading effect of the surfactants as well as spontaneous nanoparticles formation, which may be favorable characteristics of pulmonary drug delivery systems...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2020
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics13010031